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Pivotal Role of the Interaction Between Herbal Medicines and Gut Microbiota on Disease Treatment

Author(s):

Tingting Zhao, Zhe Wang , Zhilong Liu and Youhua Xu *   Pages 1 - 11 ( 11 )

Abstract:


With the recognition of the important role of gut microbiota in both health and disease progression, attempts to modulate its composition as well as its co-metabolism with the organism have attracted special attention. Abundant studies have demonstrated that dysfunction or imbalance of gut microbiota is closely with disease including endocrine diseases, neurodegenerative diseases, tumors, cardiovascular diseases, et al. Herbal medicines have been applied for preventing and treating disease worldwide for hundreds of years. Although the underlying mechanism seems to be complex, one of the important one is through modulating gut microbiota. In this review, co-metabolism between herbal medicines and microbiota, as well as the potential pathways are summarized from most recent published papers.

Keywords:

herbal medicines, gut microbiota, metabolism, mechanism.

Affiliation:

State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology , State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology , Department of Endocrinology, Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine , State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa



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