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Cardiovascular Modulating Effects of Magnolol and Honokiol, Two Polyphenolic Compounds from Traditional Chinese Medicine-Magnolia Officinalis

[ Vol. 21 , Issue. 6 ]

Author(s):

Yuan Yuan, Xiaocui Zhou, Yuanyuan Wang, Yan Wang, Xiangyan Teng* and Shuaiyu Wang*   Pages 559 - 572 ( 14 )

Abstract:


Honokiol and its isomer magnolol are poly-phenolic compounds isolated from the Magnolia officinalis that exert cardiovascular modulating effects via a variety of mechanisms. They are used as blood-quickening and stasis-dispelling agents in Traditional Chinese Medicine and confirmed to have therapeutic potential in atherosclerosis, thrombosis, hypertension, and cardiac hypertrophy. This comprehensive review summarizes the current data regarding the cardioprotective mechanisms of those compounds and identifies areas for further research.

Keywords:

Honokiol, magnolol, cardio-protection, anti-inflammatory, antioxidant, anti-proliferation, anti-apoptosis.

Affiliation:

College of Veterinary Medicine, China Agricultural University, Beijing 100193, China Animal Health and Epidemiology Center, Qingdao 266032, China Animal Health and Epidemiology Center, Qingdao 266032, China Animal Health and Epidemiology Center, Qingdao 266032, China Animal Health and Epidemiology Center, Qingdao 266032, College of Veterinary Medicine, China Agricultural University, Beijing 100193

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