Gangliang Huang* Pages 1 - 7 ( 7 )
The interaction between a sugar molecule and a target is relatively weak. By simultaneously linking multiple sugar molecules to one nanoparticle for forming the glyconanoparticle, the targeting can be greatly improved. This is due to the existence of multivalent interactions between the glyconanoparticle and the target. Based on this, by linking the drug to the glyconanoparticle, the targeted delivery of drug can be achieved. Therefore, glyconanoparticles have very important applications in drug delivery. Herein, the application of glyconanoparticles in drug delivery was summarized and analyzed, and countermeasures were put forward for the existing problems. At the same time, the prospect of delivering drugs for glyconanoparticles was predicted.
Glyconanoparticles, targeted drug delivery, multivalent interactions, prospect
Active Carbohydrate Research Institute, Chongqing Normal University, Chongqing, 401331