Application of Plasmonic Gold Nanoparticle for Drug Delivery System

Author(s):

Jin-Ho Lee and Jeong-Woo Choi*   Pages 271 - 278 ( 8 )

Abstract:

Background: Efforts in developing various colloidal nanoparticles (NPs) as theranostic probes have been promising in the biomedical field. Specifically, colloidal gold nanoparticles (GNP) have been extensively utilized as a theranostic probe for molecular imaging and drug delivery owing to their unique physiochemical properties with excellent biocompatibility.

Objective: This review outlines and discusses the progress regarding gold nanoparticle synthesis methods for controlled geometry (spherical, rod, and cage), surface functionalization (covalent and non-covalent), and associated in vitro/in vivo cytotoxicity as well as some of the interesting diagnostic (imaging) and therapeutic (photo-thermal, drug delivery) applications.

Results and Conclusion: GNP possesses several advantages compared to other traditional theranostic agents, we firmly believe that GNP based clinical approach will gain continuous interest with increasing numbers of innovations.

Keywords:

Theranostic probes, diagnostic and therapy, drug delivery, plasmon, gold nanoparticle.

Affiliation:

Department of Chemical & Biomolecular Engineering, Sogang University, #1 Shinsu-Dong, Mapo-Gu, Seoul 121-742, Department of Chemical & Biomolecular Engineering, Sogang University, #1 Shinsu-Dong, Mapo-Gu, Seoul 121-742

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